Lorazepam belongs to a group of medicines called benzodiazepines.

It’s used to treat anxiety and sleeping problems that are related to anxiety.

It can also be taken to help you relax before an operation or other medical or dental treatment. This is known as a pre-med.

It’s thought to work by increasing the levels of a calming chemical in your brain called gamma-aminobutyric acid (GABA).

Lorazepam is available on prescription only. It comes as tablets and as a liquid that you swallow.

It can also be given as an injection in hospital if you’re having a seizure or fit.

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• Lorazepam tablets and liquid start to work in around 20 to 30 minutes. The full sedating effect lasts for around 6 to 8 hours.
• The most common side effect is feeling sleepy (drowsy) during the daytime.
• It’s not recommended to take lorazepam for longer than 4 weeks.
• If lorazepam makes you feel sleepy, do not drive, ride a bike or use tools or machinery.
• Do not drink alcohol while taking lorazepam. It can make you sleep very deeply. You may have breathing problems and difficulty waking up.

Dosage and strength

Lorazepam comes as 0.5mg, 1mg and 2.5mg tablets. The liquid contains 1mg of lorazepam in each 1ml.

The usual dose is:

• anxiety in adults – 1mg to 4mg each day. Your doctor will tell you how often you need to take it
• sleeping problems in adults – 1mg to 2mg before bedtime (lorazepam will start to work in around 20 to 30 minutes)
• a pre-med for adults – 2mg to 3mg the night before the procedure and then 2mg to 4mg about 1 to 2 hours before your procedure
• a pre-med for children aged 5 years to 11 years – the dose will depend on the child’s weight
• a pre-med for children aged 12 to 17 years – 1mg to 4mg either the night before the procedure or at least 1 hour before the procedure, or both

For older people or people with liver or kidney problems, a doctor may recommend a lower dose.

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Changes to your dose

Lorazepam is usually prescribed for a short time, from a few days to 4 weeks. Your dose may go up or down until your doctor is sure you’re on the right dose.

Your doctor may gradually reduce your dose at the end of the course of treatment before you stop completely.

How to take it

Take lorazepam tablets with a drink of water. You can take them with or without food.

If you’re taking lorazepam as a liquid, the medicine will come with a plastic syringe or spoon to help you measure out the right dose. If you do not have a syringe or spoon, ask your pharmacist for one. Do not use a kitchen teaspoon as it will not measure the right amount.

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